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Table 2 Cox proportional hazards analysis of the prognostic interaction of SATB1 with SATB2 expression

From: Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer

 

Cancer specific survival

Overall survival

 
 

HR(95%CI)

p

 

p†

HR(95%CI)

p

 

p†

All SATB2 positive tumours

univariable

   

univariable

  

SATB1 neg

1,00

 

171(52)

 

1,00

 

171(67)

 

SATB1 pos

1.09(0.75-1.57)

0.649

192(64)

 

1.01(0.73-1.41)

0.932

192(77)

 
    

0.011

   

0.015

All SATB2 negative tumours

univariable

   

univariable

  

SATB1 neg

1,00

 

125(46)

 

1,00

 

125(56)

 

SATB1 pos

2.63(1.46-4.71)

0.001

22(15)

 

2.31(1.32-4.04)

0.003

22(16)

 
  

multivariable

   

multivariable

  

SATB1 neg

1,00

 

115(40)

 

1,00

 

115(48)

 

SATB1 pos

2.07(1.06-4.05)

0.034

17(12)

 

2.05(1.09-3.88)

0.026

17(13)

 
  1. Multivariable analysis included adjustment for age (>/<=75 years), gender, T-stage (I-II, III, IV), N-stage (0,1,2), M-stage (0, 1) and differentiation grade (high-intermediate vs low). p†: P-value for term of interaction by Cox multivariate analysis including SATB1 expression, SATB2 expression, and a term of interaction.