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Table 5 Odds ratios of immunohistochemical markers

From: Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors

 

Odds ratio

95% confidence interval

Significance

For differentiation of borderline and malignant tumorsa

p53*

2.1

1.2-3.8

p < 0.05

For differentiation of benign and borderline and malignant tumors combinedb

p21*

1.7

1.0-2.8

P < 0.05

bax**

2.0

1.0-3.9

P < 0.05

Metallothionein**

1.5

1.1-1.9

p < 0.05

  1. *Nuclear staining score. **Quick score.
  2. aOnly p53 was determined the significant predictor for malignant tumors during differentiation between borderline and malignant tumors.
  3. bp21, bax, and metallothionein was determined the significant predictors for borderline and malignant tumors combined during differentiation between benign and borderline and malignant tumors combined.
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Diagnostic Pathology

ISSN: 1746-1596

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