Figure 6

The relationship between BTLA-HVEM and fibrinogen-like protein 2 (FGL2) expression in sections from patients with HBV-related acute-on-chronic liver failure (HBV-ACLF). Immunofluorescence double staining demonstrated that FGL2 expression was observed in CD31⁺ endothelial cells, CD68⁺ macrophages, and CK-18⁺ bile ducts of HBV-ACLF patients. Moreover, BTLA and HVEM were co-expressed with FGL2. The arrows indicate positive cells. The nuclei were stained with DAPI, and the scale bar indicates 20 μm.