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Table 2 Summary of immunohistochemical expression of arginase-1and HepPar-1 in all the studied cases

From: The diagnostic value of arginase-1 immunostaining in differentiating hepatocellular carcinoma from metastatic carcinoma and cholangiocarcinoma as compared to HepPar-1

 

Arginase-1

HepPar-1

Negative

Positive

Total positive

Negative

Positive

Total positive

0 (%)

1+(%)

2+(%)

No (%)

0(%)

1+(%)

2+(%)

No (%)

Hepatocellular carcinoma (HCC), (no=50):

8 (16)

19 (38)

23 (46)

42 (84)

15 (30)

16 (32)

19 (38)

35 (70)

well differentiated (no=11)

0 (0)

3 (27.3)

8 (72.7)

11 (100)

0 (0)

4 (36.4)

7 (63.6)

11 (100)

moderately differentiated (no=30)

3 (10)

12 (40)

15 (50)

27 (90)

8 (26.7)

10 (33.3)

12 (40)

22 (73.3)

poorly differentiated (no=9)

5 (55.6)

4 (44.4)

0 (0)

4 (44.4)

7 (77.8)

2 (22.2)

0 (0)

2 (22.2)

Metastatic carcinoma (MC) (no=38)

37 (97.4)

1 (2.6)

0 (0)

1 (2.6)

32 (84.2)

2 (5.3)

4 (10.5)

6 (15.8)

Colonic (no=25)

25 (100)

(0)

0 (0)

0 (0)

22 (88)

1 (4)

2 (8)

3 (12)

Gastric (no=6)

6 (100)

0 (0)

0 (0)

0 (0)

3 (50)

1 (16.7)

2 (33.3)

3 (50)

Renal cell carcinoma (no=2)

2 (100)

0 (0)

0 (0)

0 (0)

2 (100)

0 (0)

0 (0)

0 (0)

Pancreas (no=2)

1 (50)

1 (50)

0 (0)

1 (50)

2 (100)

0 (0)

0 (0)

0 (0)

Lung (no=2)

2 (100)

0 (0)

0 (0)

0 (0)

2 (100)

0 (0)

0 (0)

0 (0)

Gall bladder (no=1)

1 (100)

0 (0)

0 (0)

0 (0)

1 (100)

0 (0)

0 (0)

0 (0)

Cholangiocarcinoma (no=12)

11 (91.7)

1 (8.3)

0 (0)

1 (8.3)

10 (83.3)

1 (8.3)

1 (8.3)

2 (16.7)

Non-neoplastic cirrhotic liver tissues adjacent to HCC(no=42)

0 (0)

0 (0)

42 (100)

42 (100)

0 (0)

0 (0)

42 (100)

42 (100)

Non-neoplastic liver tissue adjacent to MC (no= 9)

0 (0)

0 (0)

9 (100)

9 (100)

0 (0)

0 (0)

9 (100)

9 (100)

Normal liver tissues (no=10)

0 (0)

0 (0)

10 (100)

10 (100)

0 (0)

0 (0)

10 (100)

10 (100)

  1. HepPar-1=hepatocyte paraffin antigen-1.