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Table 2 Demographics and patients’ characteristics according to diagnosis by interdisciplinary evaluation

From: Diagnostic approach to interstitial pneumonias in a single centre: report on 88 cases

 

All

IPF/UIP

NSIP

RBILD

COP

HP

LCH

Patients (N)

74

27

14

6

10

10

7

Gender,male/female

43/31

21/6

6/8

5/1*

7/3

2/8**

2/5

Age, mean ± SE

53 ± 11

60 ± 11

51 ± 14*

44 ± 6*

58 ± 11

52 ± 10

44 ± 12*

BMI, kg/m2

26 ± 5

28 ± 5

26 ± 4

26 ± 4

26 ± 4

24 ± 3

24 ± 8**

Smoking history

  - current/ex (%)

47 (64)

18 (67)

8 (57)

6 (100)*

7 (70)

1 (10)

7 (100)*

  - never smokers

27 (36)

9 (33)

6 (43)

0 (0)

3 (30)

9 (90)

0 (0)

Pack years, mean

20.4

17

14.5

27

21

n.a.

22.5

Symptoms

  - dyspnoea (%)

65 (88)

26 (96)

13 (93)

4 (67)

7 (70)

10 (100)

5 (71)

  - cough (%)

54 (73)

22 (78)

9 (64)

3 (50)

8 (80)

8 (80)

4 (57)

Duration of symptoms, years

2.2

1.6

1.7††

1.4

0.3††

4.3**

4.2**

FVC % pred, mean ± SE

66 ± 15

61 ± 16

61 ± 9

71 ± 7

72 ± 11

57 ± 13

78 ± 19**

FEV1, % pred, mean ± SE

66 ± 14

66 ± 15

65 ± 12

77 ± 12

77 ± 13

63 ± 14

54 ± 21†

TLC, % pred, mean ± SE

78 ± 20

67 ± 14

77 ± 15

91 ± 15*

85 ± 19*

68 ± 10

98 ± 17*

PaO2, mmHg

74 ± 10

73 ± 8

73 ± 8

80 ± 8

70 ± 14

78 ± 10

72 ± 13

PaCO2, mmHg

38 ± 4

39 ± 4

36 ± 3

39 ± 3

40 ± 5

39 ± 3

37 ± 4

AaDO2, mmHg

28 ± 16

33 ± 19

30 ± 11

13 ± 6**

25 ± 12

22 ± 10

16 ± 7

  1. n.a. = not available.
  2. * p <0.005 vs IPF/UIP.
  3. ** p < 0.05 vs IPF/UIP.
  4. † p < 0.05 vs RBILD and COP.
  5. †† p < 0.05 vs HP and LCH.