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Table 1 Expression differences and clinical features of ABCG2 and V-ATPase in pathological grading and TNM staging of esophageal squamous cell carcinoma

From: ABCG2/V-ATPase was associated with the drug resistance and tumor metastasis of esophageal squamous cancer cells

Group

Cases

Expression of ABCG2

Expression of V-ATPase

-

+

++

Positive rate (%)

Statistical value

-

+

++

Positive rate (%)

Statistical value

Sex

Male

253

14

25

14

54.72

u = 188.5.0 P = 0.007

12

31

10

77.36

u = 164.0 P = 0.001

Female

13

8

5

0

38.46

9

4

0

30.77

Age

≤60

28

8

10

10

71.43

u = 408.0 P = 0.083

7

15

6

75.00

u = 439.0 P = 0.181

>60

38

14

20

4

63.16

14

20

4

63.16

pathological grading

I

15

13

0

2

13.33

χ 2 = 20.36 P = 0.000

11

2

2

26.67

χ 2 = 11.89 P = 0.003

α

24

6

17

1

75.00

6

17

1

75.00

β

27

3

13

11

88.89

4

16

7

85.19

Total

66

22

30

14

66.67

21

35

10

68.18

TNM staging

αa

27

18

9

0

33.33

χ 2 = 26.05 P = 0.000

17

10

0

39.26

χ 2 = 22.68 P = 0.000

αb

22

2

14

6

90.90

2

16

4

90.90

β

17

2

7

8

88.23

2

9

6

87.50

 

Total

66

22

29

14

66.67

 

21

35

10

68.18

Lymphatic metastasis

Yes

39

5

20

14

87.18

u = 192.5 P = 0.000

5

24

10

87.18

u = 227.0 P = 0.000

No

27

17

10

0

37.04

16

11

0

40.74