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Table 4 Proportions of TERC/C-MYC amplification types in cervical disorders

From: Genomic amplification patterns of human telomerase RNA gene and C-MYC in liquid-based cytological specimens used for the detection of high-grade cervical intraepithelial neoplasia

 

TERC positive

C-MYC positive

Histological diagnosis

CIN2+

Normal/CIN1

CIN2+

Normal/CIN1

Case no.

45

20

40

43

Abnormal nuclei (no.)

963

213

854

293

Abnormal nuclei (%)

21.1

10.2

20.9

6.2

Distribution of GCN (%)

3 copies

27.7

55.9

48.0

49.5

4 copies

31.9

25.4

35.5

39.9

5 copies

16.5

10.8

9.6

7.2

6 copies

7.1

5.6

3.9

1.7

≥ 7 copies

16.8

2.3

3.0

1.7

Distribution of TERC: CEP3 ratios (%)

< 1

4.0

5.2

  

= 1

26.9

33.8

  

> 1

69.1

61.0