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Table 4 Proportions of TERC/C-MYC amplification types in cervical disorders

From: Genomic amplification patterns of human telomerase RNA gene and C-MYC in liquid-based cytological specimens used for the detection of high-grade cervical intraepithelial neoplasia

  TERC positive C-MYC positive
Histological diagnosis CIN2+ Normal/CIN1 CIN2+ Normal/CIN1
Case no. 45 20 40 43
Abnormal nuclei (no.) 963 213 854 293
Abnormal nuclei (%) 21.1 10.2 20.9 6.2
Distribution of GCN (%)
3 copies 27.7 55.9 48.0 49.5
4 copies 31.9 25.4 35.5 39.9
5 copies 16.5 10.8 9.6 7.2
6 copies 7.1 5.6 3.9 1.7
≥ 7 copies 16.8 2.3 3.0 1.7
Distribution of TERC: CEP3 ratios (%)
< 1 4.0 5.2   
= 1 26.9 33.8   
> 1 69.1 61.0