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Table 1 Statistics of the 24 candidate biomarkers for identifying breast cancer patients from healthy individuals

From: Serum peptidome patterns of breast cancer based on magnetic bead separation and mass spectrometry analysis

Mass

Breast cancer

Health

Regulation in breast cancer

P ★

 

Meansâ–²

SD

Meansâ–²

SD

  

622.48

48.9

24.43

34.29

18.28

↑

0.0454

622.97

48.26

24.67

30.41

14.76

↑

0.013

654.73

27.08

9.66

18.02

5.6

↑

0.0048

655.23

23.48

8.61

16.35

4.46

↑

0.00827

666.78

13.96

6.64

20.73

6.29

↓

0.00821

667.12

13.07

6.56

18.81

5.77

↓

0.0146

676.83

39.48

25.42

15.69

15.75

↑

1.98E-05

698.4

116.2

35.99

76.07

27.99

↑

0.0048

698.81§

114.32

35.83

70.97

23.34

↑

0.00138

720.8§

13.59

6.5

23.41

8.61

↓

0.00199

721.4

13.31

6.39

19.92

7.96

↓

0.0165

858.11

13.28

6.03

8.11

3.76

↑

0.0182

887.23

10.15

3.38

8.33

5.93

↑

0.0222

893.99

12.58

7.56

21.87

8.11

↓

0.00218

909.06

27.78

15.1

40.15

14.33

↓

0.0127

909.75

26.61

15.1

37.89

14.06

↓

0.0222

1618.46

11.12

8.56

21.88

16.05

↓

0.017

1866.64§

6.66

5.23

12.97

7.21

↓

0.00199

2770.34

6.64

5.11

2.26

1.07

↑

0.00123

2771.86

5.73

4.78

1.48

0.68

↑

0.000427

2933.97

3.69

2.06

1.86

0.85

↑

0.0103

5963.91

0.71

0.76

0.2

0.24

↑

0.0222

7772.04

0.73

0.94

0.25

0.46

↑

0.0176

7777.16

0.8

1.01

0.3

0.51

↑

0.0406

  1. §The peptide selected for model construction.
  2. â–²Peak area.
  3. ★P value calculated with the Wilcoxon test; values lower than 0.05 suggest statistical relevance.