Figure 2

Gross and microscopic examination, and schema of the resected specimen. (A) On gross examination (inset), the cut surface revealed an encapsulated but poorly-demarcated, and predominantly solid firm mass, measuring 32 × 25 mm, which looked from grayish-blue to yellowish-white in colour, almost corresponding to the areas from pleomorphic adenoma (PA) to both ‘intraductal (ID)’ and ‘extraductal (ED)’ salivary duct carcinoma (SDC) components, associated with central hemorrhage and foci of extracapsular invasion (lower, arrows). Bar = 10 mm. (B) A scanning magnification of it showed that the PA components embedded in abundant chondroid matrix was less than 50%, with transition to the predominant (more than 50%) SDC components (H&E stains). Bar = 10 mm. (C) The schema of these tumor components (PA; blue, ID; yellow, and ED; red) was shown, likely displaying a sequential and stepwise progression.