Figure 2From: Delayed apoptosis by neutrophils from COPD patients is associated with altered bak, bcl-xl, and mcl-1 mRNA expressionExpression of Bak, Bcl-xl, and Mcl-1 mRNAās in peripheral blood neutrophils. Real-time PCR was used to determine the expression of (A) Bak, (B) Bcl-xl, and (C) Mcl-1 mRNAs in peripheral blood neutrophils. The ĪĪCt value for each mRNA was normalized to the value of the GADPH housekeeping gene mRNA. Results are meansāĀ±āSEMs for: COPD/smokers (nā=ā24); COPD/non-smokers (nā=ā23); Healthy/smokers (nā=ā24); and Healthy/non-smokers (nā=ā23). Groups were compared using two-sample t-test for Bak and Mcl-1 mRNAās, and a MannāWhitney U test for Bcl-x1 mRNA due to its non-normal distribution. * significant difference as compared with Healthy/non-smokers (pā<ā0.05); ā significant difference as compared with Healthy/smokers (pā<ā0.05).Back to article page