Table 2 EZH2 staining
EZH2 expression | Negative (score0) | Weak (score1) | Moderate (score2) | Strong (score3) | Sensitivity/Specificity |
|---|---|---|---|---|---|
Hepatocellular carcinoma (n = 44) | 0.90/0.33 | ||||
Grade I. | 2 | 6 | 4 | 0 | |
Grade II. | 1 | 12 | 7 | 2 | |
Grade III | 1 | 4 | 2 | 2 | |
Grade IV. | 0 | 1 | 0 | 0 | |
CC (n = 23) | 0.96/0.18 | ||||
Grade I. | 0 | 2 | 2 | 1 | |
Grade II. | 1 | 2 | 9 | 2 | |
Grade III | 0 | 1 | 3 | 0 | |
Hepatoblastoma (n = 31) | 2 | 6 | 9 | 14 | 0.94/0.24 |
Hepatocellular adenoma (n = 24) | 24 | 0 | 0 | 0 | 0/0 |
Biliary cystadenoma (n = 3) | 3 | 0 | 0 | 0 | 0/0 |
Metastases | NC* | ||||
Colon (n = 8) | 0 | 0 | 5 | 3 | |
Breast (n = 2) | 0 | 0 | 2 | 0 | |
Lung (n = 2) | 0 | 0 | 0 | 2 | |
Neuroendocrine (n = 3) | 3 | 0 | 0 | 0 | |
Urothel (n = 1) | 1 | ||||
Pancreas (n = 1) | 1 | ||||
Childhood tumors | NC* | ||||
Rhabdomyosarcoma (n = 4) | 0 | 1 | 2 | 1 | |
Neuroblastoma (n = 5) | 0 | 0 | 3 | 2 | |
Wilms’ tumor (n = 5) | 0 | 1 | 1 | 3 | |
Rhabdoid tumor (n = 2) | 0 | 0 | 1 | 1 | |
Non tumorous lesions | |||||
High grade dysplastic nodule (n = 15) | 15 | 0 | 0 | 0 | |
Biliary hamartoma (n = 3) | 3 | 0 | 0 | 0 | |
Caroli’s disease (n = 3) | 3 | 0 | 0 | 0 |