Table 1 Expression of CLDN2, CLDN6, CLDN11 and clinicopathological characteristics in gastric cancer patients
Item | n | CLDN2(+) | CLDN2(-) | P | n | CLDN6(+) | CLDN6(-) | P | n | CLDN11(+) | CLDN11(-) | P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gastric cancer tissue | 40 | 10 | 30 | <0.001 | 40 | 22 | 18 | 0.045 | 40 | 32 | 8 | 0.004 |
Adjacent tissue | 28 | 19 | 9 | 28 | 22 | 6 | 28 | 13 | 15 | |||
Gender | ||||||||||||
Male | 31 | 9 | 22 | 0.404* | 31 | 18 | 13 | 0.705* | 31 | 26 | 5 | 0.645* |
Female | 9 | 1 | 8 | 9 | 4 | 5 | 9 | 7 | 2 | |||
Age (year) | ||||||||||||
≤60 | 17 | 4 | 13 | 1.000* | 17 | 8 | 9 | 0.385 | 17 | 15 | 2 | 0.677* |
>60 | 23 | 6 | 17 | 23 | 14 | 9 | 23 | 18 | 5 | |||
Histological grade | ||||||||||||
Well -differentiated | 11 | 3 | 8 | 1.000* | 11 | 6 | 5 | 1.000* | 11 | 9 | 2 | 1.000* |
Moderately and poor differentiated | 27 | 7 | 20 | 27 | 15 | 12 | 27 | 21 | 6 | |||
Lymph node metastasis | ||||||||||||
+ | 25 | 7 | 18 | 0.715* | 25 | 14 | 11 | 0.870 | 25 | 19 | 6 | 0.224* |
- | 15 | 3 | 12 | 15 | 8 | 7 | 15 | 14 | 1 |