The expression of V-ATPase is associated with drug resistance and pathology of non-small-cell lung cancer

Diagnostic Pathology

Table 4 The correlation of V-ATPase expression with drug sensitivity (resistance) in squamous cell lung cancer

V-ATPase	Cyclophosphamide					Gemcitabine					Doxorubicin					Paclitaxel					Cisplatin
V-ATPase	R	LS	MS	HS	p value	R	LS	MS	HS	p value	R	LS	MS	HS	p value	R	LS	MS	HS	p value	R	LS	MS	HS	p value
_	0	3	2	2	χ2 =30.12	0	2	3	2	χ2 = 24.143	0	2	0	5	χ2 = 34.11	0	0	0	0	χ2 = 10.03	0	0	2	5	χ2 = 32.88
+	4	7	2	0	p = 0.00	3	6	4	0	p = 0.000	0	4	5	1	p = 0.000	0	1	5	7	p = 0.124	3	3	6	1	p = 0.000
++	20	3	0	0	rs = −0.742	12	11	0	0	rs = −0.607	0	9	1	0	rs = −0.630	4	3	5	11	rs = −0.349	17	4	1	1	rs = −0.707

R: Resistance; LS: Low sensitivity; MS: Moderate sensitivity; HS: High sensitivity.

ISSN: 1746-1596