Intravascular papillary endothelial hyperplasia: histomorphological and immunohistochemical features

Diagnostic Pathology

Table 2 Immunohistochemical staining distribution

Case	CD31*	CD34*	FVIII**	Type IV Collagen***	SMA****	MSA****	CD105	Ki67
Case 1	+	+	+	+	+	+	-	≤1%
Case 2	+	+	+	+	+	+	-	≤1%
Case 3	+	+	-	+	+	+	-	≤2%
Case 4	+	+	+	+	+	+	-	≤8%
Case 5	+	+	-	-	-	-	-	≤5%
Case 6	+	+	+	+	+	+	-	≤7%
Case 7	+	+	-	+	+	+	-	2%
Case 8	+	+	-	-	-	-	-	3%
Case 9	+	+	+	+	+	+	-	3%
Case 10	+	+	+	+	+	+	-	1%

* They stained the immature endothelium which covers multiple small papillary structures (lining endothelial cells), and also mature well formed vessels.
** Positive staining was seen in mature lesions.
***Positive staining in the basement membrane of the endothelial vessel wall.
****Positive staining was seen only surrounding wall of mature well formed vessels.

ISSN: 1746-1596