Table 3 Association between rs11178 and rs2227631 SNPs and the risk of steroid-induced ONFH
SNP ID | Genotype | Cases | Control | Codominant | Dominant | Recessive | Overdominant | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | ||||
rs11178 | C/C | 21 | 24 | 1.00 | 0.15 | 1.00 | 0.07 | 1.00 | 0.23 | 1.00 | 0.55 |
T/C | 52 | 52 | 0.50 | 0.39 | 0.66 | 0.80 | |||||
(0.20-1.23) | (0.16- 1.08) | (0.28-1.47) | (0.39-1.65) | ||||||||
T/T | 20 | 27 | 0.38 | 0.46 | 0.60 | 0.81 | |||||
(0.13-1.07) | (0.19-1.07) | (0.26-1.40) | (0.39-1.68) | ||||||||
rs2227631 | G/G | 34 | 33 | 1.00 | 0.04 | 1.00 | 0.18 | 1.00 | 0.02 | 1.00 | 0.83 |
A/G | 43 | 53 | 0.74 | 0.60 | 0.24 | 1.08 | |||||
(0.34-1.63) | (0.28-1.27) | (0.07-0.80) | (0.53-2.20) | ||||||||
A/A | 9 | 14 | 0.20 | 0.53 | 0.22 | 1.05 | |||||
(0.05-0.73) | (0.30-0.94) | (0.06-0.77) | (0.47-2.12) | ||||||||