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Table 2 Comparison of results obtained by different methods for amplified cases without HSR (n = 28)

From: Validation of a new classifier for the automated analysis of the human epidermal growth factor receptor 2 (HER2) gene amplification in breast cancer specimens

Manual scoring

Tile-sampling analysis

Nuclei-sampling analysis

Automated analysis

After human correction

< 2.0

2.0 – 2.2

> 2.2

< 2.0

2.0 – 2.2

> 2.2

< 2.0

2.0 – 2.2

> 2.2

> 2.2

0

0

28

3

4

21

1

3

24

  1. HSR = Homogeneously Staining Regions.
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Diagnostic Pathology

ISSN: 1746-1596

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