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Table 5 Copy number variations of mtDNA in late-stage gastric cancer — univariate associations with clinicopathological characteristics

From: Variable copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in advanced gastric cancer patients

Characteristics

     Copy number <3.61

 

     Copy number >5.35

 

OR*(95% CI)

P

OR*(95% CI)

P

Male vs. Female

1.57 (0.31-7.99)

0.59

2.79 (0.37-20.82)

0.32

Age1

0.67 (0.15-2.89)

0.59

1.33 (0.25-7.01)

0.73

Tumor localization2

0.44 (0.13-1.45)

0.18

0.70 (0.19-2.616)

0.60

Tumor size3

1.86 (0.78-4.42)

0.16

2.10 (0.79-5.57)

0.14

Tumor invasion4

1.13 (0.53-2.41)

0.74

1.16 (0.50-2.69)

0.73

Lymph node metastasis

27.00 (2.89-252.62)

0.004

13.50 (1.34-135.98)

0.03

Survival status5

3.11 (0.66-14.60)

0.15

6.42 (1.09-37.74)

0.04

  1. *OR: odds ratio with 95% confidence interval; 1Age (per 10 years); 2Tumor localization (gastric cardia; gastric body; gastric antrum); 3Tumor size (≤3 cm; >3 cm and ≤5 cm; >5 cm); 4Tumor invasion (T1; T2; T3; T4); 5Survival status (Alive vs. Dead). The cases with 3.61-5.35 mtDNA copies were used as reference.