Table 4 Relationship between Topo II expression and chemosensitivity
From: The association between chemosensitivity and Pgp, GST-π and Topo II expression in gastric cancer
Drug | Chemosensitivity | Cases (n) | Topo II expression | χ 2 | P | |
|---|---|---|---|---|---|---|
Positive(n) | Negative(n) | |||||
HCPT | Sensitive | 32 | 27 | 5 | 9.224 | 0.009 |
Resistant | 43 | 24 | 19 | |||
CDDP | Sensitive | 33 | 23 | 10 | 0.787 | 0.635 |
Resistant | 42 | 28 | 14 | |||
5-FU | Sensitive | 38 | 29 | 9 | 2.326 | 0.149 |
Resistant | 37 | 26 | 11 | |||
ADM | Sensitive | 31 | 26 | 5 | 7.250 | 0.015 |
Resistant | 44 | 25 | 19 | |||
MMC | Sensitive | 28 | 25 | 3 | 6.843 | 0.019 |
Resistant | 47 | 26 | 21 | |||