Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors

Diagnostic Pathology

Table 4 PRMT5 expression in NET

		Cytoplasmic high PRMT5, n (%)	P	Nuclear high PRMT5, n (%)	P	N^a
Age	≤60 years (n = 59)	8 (6.3)	0.43	12 (9.4)	0.61	128
Age	>60 years (n = 69)	12 (9.4)	0.43	19 (14.8)	0.61	128
Gender	Female (n = 62)	7 (5.4)	0.33	18 (14.0)	0.16	129
Gender	Male (n = 67)	14 (10.9)	0.33	13 (10.1)	0.16	129
Size	≤3 cm (n = 69)	9 (8.3)	0.71	19 (17.6)	0.76	108
Size	>3 cm (n = 39)	7 (6.5)	0.71	11 (10.2)	0.76	108
Stage	I (n = 69)	12 (12.0)	0.48	17 (17.0)	0.42	100
Stage	II-IV (n = 31)	7 (7.0)	0.48	10 (10.0)	0.42	100
Histology	Carcinoid (n = 63)	6 (4.5)	0.04	22 (16.5)	0.02	133
Histology	HG-NET (n = 70)	16 (12.0)	0.04	10 (7.5)	0.02	133
Survival	Yes (n = 46)	8 (8.0)	0.923	16 (16.0)	0.02	100
Survival	No (n = 54)	9 (9.0)	0.923	8 (8.0)	0.02	100

Abbreviations: Neg negative, N number of cases, HG-NET high grade neuroendocrine tumors.
^aReflects total number of cases with available annotations.

ISSN: 1746-1596