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Table 2 Histological classification of oropharyngeal carcinomas

From: Histological subtypes and characteristic structures of HPV-associated oropharyngeal carcinoma; study with Japanese cases

Histological typea Number of cases HPV-OPCb nHPV-OPCc P value
Conventional SCC     
KSCC 22(33.3%) 1(4.5%) 21(95.5%)  
NKSCC 21(31.8%) 15(71.4%) 6(28.6%) <0.01
HSCC 11(16.7%) 7(63.6%) 4(36.4%) <0.01
Variant     
Basaloid SCC 3(4.5%) 3(100.0%) 0(0.0%)  
Papillary SCC 3(4.5%) 2(66.7%) 1(33.3%)  
Lymphoepithelial carcinoma 2(3.0%) 1(50.0%) 1(50.0%)  
Unclassified 4(6.1%) 2(50.0%) 2(50.0%)  
Total 66 31(47.0%) 38(57.0%)  
  1. aHistological Type: KSCC, keratinizing SCC; NKSCC, nonkeratinizing SCC; HSCC, hybrid SCC.
  2. bHPV-OPC, HPV-associated oropharyngeal carcinoma.
  3. cnHPV-OPC, HPV-unassociated oropharyngeal carcinoma.