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Table 3 Summary of Cox regression analysis of overall survival duration of P27 nuclear and cytoplasm expression

From: Decreased P27 protein expression is correlated with the progression and poor prognosis of nasopharyngeal carcinoma

Parameter Univariate analysis Multivariate analysis
  P HR 95% CI P HR 95% CI
Gender       
Male vs. female 0.485 0.488 0.665-2.361    
Age       
≥50 vs. <50 years 0.787 0.073 0.620-1.881    
Family tumor history       
Yes vs. No 0.349 0.877 0.000-28.401    
Smoking       
Yes vs. No 0.387 0.748 0.368-1.474    
Chemotherapy       
Yes vs. No 0.700 1.153 0.560-2.372    
Radiotherapy       
Yes vs. No 0.005 0.369 0.184-0.742 0.944 1.032 0.431-2.469
T classification       
T1-T2 vs. T3-T4 0.000 13.289 1.884-8.223 0.014 6.032 1.225-6.067
N classification       
N0-N1 vs. N2--N3 0.000 2.950 1.662.-5.237 0.240 1.379 0.720-3.700
M classification       
M0 vs. M1 0.000 35.042 5.031-24.906 0.001 10.438 1.803-11.112
TNM Clinical stage       
I-II vs. III-IV 0.000 19.386 3.592-27.943 0.051 3.795 0.992-14.238
P27 expression       
High expression vs. low expression 0.030 4.724 0.290-0.938 0.682 0.168 0.471-1.637