Table 4 Univariate and multivariate analysis of prognostic factors of OS in advanced gastric cancer
From: Correlation of hK6 expression with tumor recurrence and prognosis in advanced gastric cancer
Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
Variable | HR | 95% CI | P | HR | 95% CI | P |
Gender F/M | 1.35 | 0.80-2.25 | 0.26 | – | – | – |
Age < 60/≥60 yr | 1.59 | 0.95-2.67 | 0.08 | – | – | – |
Tumor site | – | – | 0.17 | – | – | – |
body/fundus | 0.47 | 0.20-1.09 | 0.078 | – | – | – |
antrum/fundus, body | 0.57 | 0.29 -1.13 | 0.11 | – | – | – |
Tumor size < 5/ ≥5 cm | 1.72 | 1.02-2.90 | 0.043 | – | – | 0.57 |
grade Well/Poorly | 0.57 | 0.26-1.27 | 0.17 | – | – | – |
T stage | – | – | 0.004 | – | – | 0.019 |
T3/T2 | 1.60 | 0.66-3.89 | 0.30 | 0.83 | 0.33–2.12 | 0.70 |
T4/T2,T3 | 3.36 | 1.38–8.15 | 0.007 | 1.86 | 0.73–4.70 | 0.19 |
N stage N0,N1/N2,N3 | 2.87 | 1.57–5.21 | 0.001 | – | – | 0.12 |
Vascular−/+ | 1.23 | 0.65-2.34 | 0.52 | – | – | – |
Perineural−/+ | 1.32 | 0.71-2.43 | 0.38 | – | – | – |
Margin−/+ | 1.29 | 0.72-2.31 | 0.40 | – | – | – |
TNM stage I,II/III,IV | 4.05 | 2.04– 8.03 | <0.001 | 2.99 | 1.45–6.16 | 0.003 |
hK6−/+ | 2.88 | 1.40-5.92 | 0.004 | 2.66 | 1.25–5.63 | 0.011 |