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Table 7 Associations between different clinicopatholiogical features and genotype frequency of GG in rs6010620, and CC in rs2297440 of RTEL1 gene in glioma patients ( n= 75, 73, respectively)

From: RTEL1 tagging SNPs and haplotypes were associated with glioma development

Clinicopatholiogical features

GG frequency

P value

CC frequency

P value

 

n(%)

 

n(%)

 

WHO grade

 

I

12 (16.0)

>0.05

11 (14.7)

>0.05

II

35 (46.7)

 

35 (56.2)

 

III

12 (16.0)

 

13 (17.8)

 

IV

16 (21.3)

 

14 (19.2)

 

Age

 

≥40

36 (48.0)

NS

40 (54.8)

NS

<40

39 (52.0)

 

33 (45.2)

 

Gender

 

Male

30 (40.0)

NS

31 (42.5)

NS

Female

45 (60.0)

 

42 (57.5)

 

KPS

 

≥70

72 (96.0)

>0.05

70 (95.9)

>0.05

<70

3 (4.0)

 

3 (4.1)

 
  1. NS not significant, KPS Karnofsky performance score.