Table 2 Association between EMT-related proteins and clinicopathological variables
Cell differentiation | p-value | TNM stage | p-value | |||
|---|---|---|---|---|---|---|
Poorly | Well and moderately | I-II | III-IV | |||
(%) | (%) | (%) | (%) | |||
Loss of epithelial protein expression | ||||||
Cytokeratin | 8(24.2) | 16(25.8) | 0.867 | 11(21.6) | 13(29.5) | 0.372 |
E-cadherin | 19(57.6) | 35(56.5) | 0.916 | 29(56.9) | 25(56.8) | 0.997 |
TTF-1 | 20(60.6) | 17(27.4) | 0.002 | 16(31.4) | 21(47.4) | 0.103 |
Acquisition of mesenchymal protein expression | ||||||
β-catenin | 19(57.6) | 26(41.9) | 0.146 | 23(45.1) | 22(50.0) | 0.633 |
Vimentin | 18(54.5) | 20(32.3) | 0.035 | 14(27.5) | 24(54.5) | 0.007 |
Snail | 26(78.7) | 31(50.0) | 0.006 | 29(56.9) | 28(63.6) | 0.502 |
Twist | 25(75.8) | 40(64.5) | 0.262 | 35(68.6) | 30(68.2) | 0.963 |
CD44 | 20(60.6) | 19(30.6) | 0.005 | 22(43.1) | 17(38.6) | 0.657 |