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Table 4 Cox proportional hazard regression model analysis

From: Prognostic impact of TAZ and β-catenin expression in adenocarcinoma of the esophagogastric junction

Factors Univariate analysis Multivariate analysis
  HR (95% CI) P-value HR (95% CI) P-value
TAZ
Positive vs. Negative 2.740 (1.791-4.192) <0.001* 1.879 (1.097-3.218) 0.022*
β-catenin (nuclear)
Positive vs. Negative 1.572 (1.028-2.402) 0.037*   
β-catenin (membranous)
Abnormal vs. Normal 2.153 (1.377-3.367) <0.001*   
TAZ & β-catenin (nuclear)
Positive vs. All others 2.482 (1.606-3.837) <0.001*   
TAZ & β-catenin (membranous)
Abnormal vs. All others 3.458 (1.732-6.908) <0.001*   
TAZ & β-catenin (nuclear and membranous)
Abnormal vs. All others 3.330 (2.082-5.328) <0.001* 1.899 (1.053-3.423) 0.033*
Tumor size (diameter)
≥ 3 cm vs. <3 cm 1.490 (0.886-2.506) 0.132   
Lymph node status
Positive vs. Negative 1.548 (1.006-2.383) 0.047*   
Tumor differentiation
Poorly vs. Well-differentiated 2.165 (1.419-3.304) <0.001* 1.870 (1.216-2.877) 0.004*
Age (years)
≥ 60 vs. < 60 1.216 (0.782-1.890) 0.386   
Gender
Male vs. Female 1.687 (0.918-3.102) 0.092   
Invation of serosa
Positive vs. Negative 1.355 (0.893-2.057) 0.154   
  1. *Statistically significant.