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Table 4 Cox proportional hazard regression model analysis

From: Prognostic impact of TAZ and β-catenin expression in adenocarcinoma of the esophagogastric junction

Factors

Univariate analysis

Multivariate analysis

 

HR (95% CI)

P-value

HR (95% CI)

P-value

TAZ

Positive vs. Negative

2.740 (1.791-4.192)

<0.001*

1.879 (1.097-3.218)

0.022*

β-catenin (nuclear)

Positive vs. Negative

1.572 (1.028-2.402)

0.037*

  

β-catenin (membranous)

Abnormal vs. Normal

2.153 (1.377-3.367)

<0.001*

  

TAZ & β-catenin (nuclear)

Positive vs. All others

2.482 (1.606-3.837)

<0.001*

  

TAZ & β-catenin (membranous)

Abnormal vs. All others

3.458 (1.732-6.908)

<0.001*

  

TAZ & β-catenin (nuclear and membranous)

Abnormal vs. All others

3.330 (2.082-5.328)

<0.001*

1.899 (1.053-3.423)

0.033*

Tumor size (diameter)

≥ 3 cm vs. <3 cm

1.490 (0.886-2.506)

0.132

  

Lymph node status

Positive vs. Negative

1.548 (1.006-2.383)

0.047*

  

Tumor differentiation

Poorly vs. Well-differentiated

2.165 (1.419-3.304)

<0.001*

1.870 (1.216-2.877)

0.004*

Age (years)

≥ 60 vs. < 60

1.216 (0.782-1.890)

0.386

  

Gender

Male vs. Female

1.687 (0.918-3.102)

0.092

  

Invation of serosa

Positive vs. Negative

1.355 (0.893-2.057)

0.154

  
  1. *Statistically significant.