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Table 1 Reported cases of biphasic malignant adenomyoepithelioma

From: Malignant adenomyoepithelioma combined with adenoid cystic carcinoma of the breast: a case report and literature review

Reference

No. of cases

Age (year)

Size (cm)

Histologic appearance of malignancy

Presence of metastasis

Hayes [5]

3

77 ~ 93

3.2 ~ 14.0

One epithelial-myoepithelial carcinoma with chondrosarcoma

1 lung

One epithelial-myoepithelial carcinoma

1 lost to follow up

One epithelial-myoepithelial carcinoma/ACC like

 

Ahmed, et al. [6]

1

71

1.0

Nests and cords of both epithelial and myoepithelial tumor cells

None

Qureshi, et al. [10]

1

65

13

Epithelial glandular structures and myoepithelial spindle areas.

None

Hungermann, et al. [11]

1

60

Not reported

Biphasic malignancy with well-developed tubular structures

Not reported

Simpson, et al. [12]

1

50

4.0

Mixed osteogenic, spindle cell, and carcinomatous differentiation

Lung

Kiaer, et al. [13]

1

46

2.0

Peripherally proliferating myoepithelial cells and luminally localized eosinophilic cuboidal and columnar cells.

None

Pauwels, et al. [14]

1

49

Not reported

A proliferation of tubules composed of epithelial cells surrounded by myoepithelial cells with high mitotic figures and focal atypia

None

Petrozza, et al. [15]

1

60

2.0

Focal epithelial-like component with high mitotic figures and partial myoepithelial-like component with atypia and high mitotic figures

None

Rasbridge, et al. [16]

5

39 ~ 76

1.3 ~ 4.5

Contain areas of invasive malignant cells or foci of cellular atypia and increased mitotic activity.

1 brain

Trojani, et al. [17]

1

51

2.0

Bicellular pattern of epithelial and myoepithelial cells

lung

Yang and Wang, et al.(current case)

1

61

1.6

Epithelial-myoepithelial carcinoma

None

  1. ACC: adenoid cystic carcinoma.