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Table 5 Copy number variations of mtDNA in late-stage laryngeal cancer — univariate associations with clinicopathological characteristics

From: Low copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in early-stage laryngeal cancer patients

Characteristics

Copy number <4.02

 

Copy number >5.42

 

OR*(95% CI)

P

OR*(95% CI)

P

Male vs. Female

8.83 (0.74-105.58)

0.09

3.58 (0.46-28.17)

0.23

Age

0.99 (0.93-1.06)

0.76

0.97 (0.91-1.04)

0.37

Differentiation1

0.37 (0.08-1.81)

0.22

0.36 (0.07-1.84)

0.22

Tumor invasion2

1.05 (0.48-2.33)

0.90

0.78 (0.35-1.74)

0.54

LNM3

1.57 (0.48-5.12)

0.45

1.37 (0.41-4.56)

0.61

Smoking history4

0.78 (0.19-3.21)

0.73

0.49 (0.12-2.04)

0.33

Survival status5

0.64 (0.20-2.08)

0.45

1.05 (0.32-3.47)

0.94

  1. *OR: odds ratio with 95% confidence interval; 1Differentiation (well or moderate; poor or undifferentiation); 2Tumor invasion (T1; T2; T3; T4); 3LNM (lymph node metastasis); 4Smoking history (at least 10 pack-years); 5Survival status (Alive vs. Dead); The cases with 4.02-5.42 mtDNA copies were used as reference.
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Diagnostic Pathology

ISSN: 1746-1596

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