Table 2 Specificities and sensitivities of “SM invasion-associated” pathologic factors and combinations of two and three factors
From: Poorly differentiated component in gastric pinch biopsies predicts submucosal invasion
“SM invasion- related” pathologic factors | Specificity (95% CI) | Sensitivity (95% CI) |
|---|---|---|
Single factors | ||
Poorly differentiated tumor | 94.3% (80.64 - 98.78) | 36.7% (22.04 - 54.25) |
Cribriform pattern | 98.3% (85.71 - 99.82) | 16.7% (7.42 - 33.3) |
Papillary feature | 94.8% (80.64 - 98.78) | 23.3% (11.9 - 40.67) |
IEND | 93.1% (78.31 - 98.05) | 40% (24.76 - 98.78) |
Combinations of two factors | ||
Poorly differentiated tumor + IEND | 100% (88.58 - 100) | 15% (6.38 - 31.38) |
Papillary feature + IEND | 100% (88.58 - 100) | 11.7% (4.42 - 27.31) |
Cribriform pattern + IEND | 100% (88.58 - 100) | 8.3% (2.66 - 23.24) |
Cribriform pattern + papillary feature | 100% (88.58 - 100) | 6.7% (1.88 - 21.06) |
Poorly differentiated tumor + papillary feature | 100% (88.58 - 100) | 5% (1.18 - 18.79) |
Poorly differentiated tumor + cribriform pattern | 98.3% (85.71 - 99.82) | |
Combinations of three factors | ||
Cribriform pattern + papillary feature + poorly differentiated tumor | 100% (88.58 - 100) | 5% (1.18 - 18.79) |
Cribriform pattern + IEND + poorly differentiated tumor | 100% (88.58 - 100) | 3.3% (0.6 - 11.08) |