Table 2 Clinical characteristics of 94 prostate cancer patients with rectal involvement (RI)
From: Factors associated with the survival of prostate cancer patients with rectal involvement
Clinical characteristics | Synchronous rectal involvement at first cancer diagnosis | Metachronous diagnosis of rectal involvement | Total |
|---|---|---|---|
(n = 63) | (n = 31) | (n = 94) | |
Age at rectal involvement | 72(57-86)(63) | 75(47-94)(27) | 72.04(47-94)(90) |
PSA at rectal involvement(ng/ml)# | 113(3.9-7650) | 32.75(0.008-1173) | 463.10(0.008-7650) |
Interval between primary tumor diagnosis and RI(months) & Race | 0 | 40(6-216) | 10.5(0-216) |
Japan | 46 | 16 | 62 |
USA | 4 | 7 | 11 |
China | 4 | 1 | 5 |
Brazil | 2 | 0 | 2 |
France | 0 | 1 | 1 |
Qatar | 1 | 0 | 1 |
Pathological grade of RI | |||
well differentiated | 2 | 0 | 2 |
moderately differentiated | 10 | 2 | 12 |
poorly differentiated | 43 | 20 | 63 |
ND | 8 | 9 | 17 |
Histology of prostate cancer RI | |||
Prostate adenocarcinoma | 61 | 29 | 90 |
Mixed type | 4 | 2 | 6 |
Tumor extent at diagnosis of RI | |||
RI only | 20 | 5 | 25( |
Extrarectal metastases | 28 | 16 | 44 |
ND | 15 | 10 | 25 |
Prior therapy | |||
Hormonal therapy | 0 | 28 | 28 |
Initial prostatectomy or radical radiotherapy | 0 | 7 | 7 |
TURP | 0 | 4 | 4 |
Type of rectal involvement | |||
I | 7 | 2 | 9 |
II | 34 | 10 | 44 |
III | 8 | 4 | 12 |
IV | 3 | 8 | 11 |
ND | 12 | 6 | 18 |
Clinical symptoms | |||
Dysuria | 14 | 4 | 18 |
Dyschezia | 47 | 17 | 64 |
Hydronephrosis | 14 | 3 | 17 |
Rectum bleeding | 14 | 9 | 23 |
bowl obstruction | 5 | 3 | 8 |
Misdiagnosized before therapy* | 18 | 3 | 21 |
Treatment modalities after diagnosis of RI | |||
colostomy | 9 | 10 | 19 |
TPE | 11 | 1 | 12 |
RR | 6 | 3 | 9 |
RT | 9 | 4 | 13 |
HT | 63 | 3 | 66 |
chemotherapy | 0 | 3 | 3 |
TPE + HT@ | 12 | 0 | 12 |
(RR or RT or TURP) + HT | 12 | 0 | 12 |