From: Clinicopathologic features of triple negative breast cancers: an experience from Pakistan
Variable | n = 205 |
---|---|
Age at dignosis | Â |
Mean ± SD (years) | 48.4 ± 12.3 |
Age specific groups, N (%) | Â |
< 30Â years | 15 (7.3%) |
31-40Â years | 47 (22.9%) |
41-50 years | 61 (29.8%) |
51-70 years | 70 (34.1%) |
> 70 years | 12 (5.9%) |
Tumor size | Â |
Mean ± SD (mm) | 38.2 ± 16.2 |
Size specific groups, n (%) | Â |
≤ 2.0 cm (pT1) | 14 (12.7%) |
2.0-5.0Â cm (pT2) | 81 (73.6%) |
> 5.0Â cm (pT3) | 15 (13.6%) |
Without surgery/trucut biopsy$ | 95 |
Histological type, n (%) | Â |
Infiltrating ductal carcinoma (NOS) | 158 (77.1%) |
Infiltrating lobular carcinoma | 05 (2.4%) |
Metaplastic carcinoma | 22 (10.7%) |
Invasive papillary carcinoma | 07 (3.4%) |
Infiltrating carcinoma with medullary features | 12 (5.9%) |
Missed ductal and lobular carcinoma | 01 (0.5%) |
Histologic grade, n (%) | Â |
Grade I (well differentiated) | Â |
Grade II (moderately differentiated) | Â |
Grade III (poorly differentiated) | 10 (4.9%) |
65 (31.7%) | |
130 (63.4%) | |
Lymphovascular invasion, n (%) | Â |
Present | Â |
Not present | Â |
Cannot be assessed$ | 30 (27.3%) |
80 (72.7%) | |
95 | |
Necrosis, n (%) | Â |
Geographic necrosis involving > 40% of tumor |  |
Necrosis involving < 40% of tumor |  |
Necrosis is absent | 34 (30.9%) |
Cannot be completely assessed$ | 72 (65.5%) |
04 (3.6%) | |
95 | |
Lymphocytic infiltration, n (%) | Â |
Extensive lymphocytic infiltration | 21 (19.1%) |
Mild to moderate lymphocytic infiltration | 89 (80.9%) |
Cannot be completely assessed$ | 95 |
Lymph node status, n (%) | Â |
Negative lymph nodes (N0) | 57 (51.8%) |
1-3 positive lymph nodes (N1) | 24 (21.8%) |
4-9 positive lymph nodes (N2) | 11 (10.0%) |
≥ 10 positive lymph nodes (N3) | 18 (16.4%) |
Lymph nodes dissection not done | 95 |
Extranodal extension, n (%) | Â |
Present | Â |
Not present | 15 (13.6%) |
Lymph nodes dissection not done | 95 (86.4%) |
95 | |
Ki-67 proliferation index | Â |
Mean ± SD (%) | 45.2 ± 25.2 |
Ki-67 proliferation index, (categories), n (%) | Â |
≤ 15% (low) |  |
16-30% (Intermediate) | Â |
>30% (High) | 32 (15.6%) |
37 (18.0%) | |
136 (66.3%) | |
Type of surgery n (%) | Â |
Modified radical mastectomy | Â |
Breast conservation surgery | Â |
Surgery not done/trucut biopsy | 90 (43.9%) |
15 (7.3%) | |
95 (46.3%) | |
Laterality n (%) | Â |
Right | 94 (45.9%) |
Left | 111 (54.1%) |