Table 1 Relationship between miR-25 expression level and clinicopathologic parameters of hepatocellular carcinoma

Gender

  Male

81

8.34 ± 4.85

  Female

50

8.11 ± 4.63

0.62

Age at diagnosis(year)

  ≤50

53

8.01 ± 5.11

  >50

78

8.49 ± 3.89

0.21

Tumor size(cm)

  ≤5

62

7.99 ± 5.13

  >5

69

9.01 ± 3.79

0.13

Tumor number

  Solitary

70

8.13 ± 4.34

  Multiple

61

8.57 ± 4.89

0.51

TNM stage

  I-II

72

6.34 ± 3.12

  III-IV

59

11.01 ± 5.61

0.01

Vein invasion

  Presence

79

9.12 ± 4.89

  Absence

52

7.31 ± 4.19

0.24

Cirrhosis

  Negative

44

7.12 ± 3.19

  Positive

87

8.89 ± 5.38

0.17

Hepatitis B virus infection

  Negative

42

6.17 ± 4.65

  Positive

89

9.21 ± 4.13

0.09

Serum AFP level (ng/ml)

  ≤25

54

6.02 ± 3.87

  >25

77

10.99 ± 5.44

0.02