Skip to main content

Table 1 Study characteristics of published cohort and case–control studies on egg intake and ovarian cancer

From: Cruciferous vegetables consumption and the risk of ovarian cancer: a meta-analysis of observational studies

Author publication year

Country

Study period

Study design

No. of subjects

Cases

FFQ used for dietary assessment

Confounders for adjustment

La Vecchia C1987

Italy

1979-1986

Hospital-based case–control study

1,380

445

Yes

Age, interviewer, marital status, social class, education, parity, age at first birth, age at menarche, menopausal status, age at menopause, BMI, oral contraceptive and other female hormone use, retinol and carotene indices, added score of fat consumption and alcohol intake

Engle A 1991

USA

1984-1989

Hospital-based case–control study

212

72

Yes

Age and smoking status

Fairfield KM 2001

USA

1976-1996

Population-based cohort study

80,326

527

Yes

Age, BMI, duration of oral contraception use, smoking history, parity, history of tubal ligation, total energy, and dietary fiber

Zhang M 2002

China

1999–2000

Hospital-based case–control study

906

254

Yes

Age at interview, education, living area, BMI, smoking, alcohol drinking, tea drinking, family income, marital and menopause status, parity, tubal ligation, oral contraceptive use, physical activity, family history of ovarian cancer, total energy intake, fruit, milk, fish, meat, egg intake

Pan SY 2004

Canada

1994-1997

Case–control study population-based

2,577

442

Yes

Age, province of residence, education, alcohol consumption, cigarette pack-years, BMI, total caloric intake, recreational physical activity, number of live births, menstruation years, and menopause status

Larsson SC 2004

Sweden

1987–1990

Population-based cohort study

61,084

266

Yes

Age, BMI, educational level, parity, oral contraceptive use, fish consumption, and dietary lactose intake, consumption of total fruit

Mommers M 2005

Netherlands

1986-1997

Population-based cohort study

62,573

252

Yes

Age, height, current cigarette smoker, duration of cigarette smoking, number of cigarettes smoked daily, duration of oral contraceptive use, parity, total fruit intake; total vegetable intake; all individual fruit or vegetable items listed for all other individual fruit or vegetable item

Sakauchi F 2007

Japan

1988-2003

Population-based cohort study

64,327

54

Yes

Age, menopausal status, number of pregnancies, history of sex hormone use, BMI, physical activity, and education

Chang ET 2007

USA

1995-2003

Population-based cohort study

97,275

280

Yes

Age, race, total energy intake, parity, oral contraceptive use, strenuous exercise, wine consumption, and menopausal status/hormone therapy use

Kolahdooz F 2009

Australia

1990-1993

Population-based case–control study

1,460

683

Yes

Age, oral contraceptive use, parity, education after high school, and energy intake

Bosetti C 2012

Italy and Switzerland

1991-2009

Hospital-based case–control study

3,442

1,031

Yes

Age, study center, year of interview, education, BMI, alcohol drinking, tobacco smoking, and total energy intake

  1. BMI = body mass index; NR = not reported; FFQ = food frequency questionnaire.
  2. The methodological qualities of the included studies were conducted by the Newcastle-Ottawa Scale (NOS) Assessment.