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Table 2 Comparison of mutation frequencies of the PIK3CA oncogene detected by three testing methods

From: Diagnostic application of PIK3CA mutation analysis in Chinese esophageal cancer patients

ME-Liquidchip vs Sanger sequencing     ME-Liquidchip vs Pyrosequencing     Sanger sequencing vs Pyrosequencing    
ME-Liquidchip     ME-Liquidchip     Sanger sequencing    
Sanger sequencing WT Mut Total Pyrosequencing WT Mut Total Pyrosequencing WT Mut Total
WT 94 5 99 WT 94 6 100 WT 99 1 100
Mut 0 7 7 Mut 0 6 6 Mut 0 6 6
Total 94 12 106 Total 94 12 106 Total 99 7 106
  1. The McNemar Test, ME-Liquidchip vs Sanger sequencing, ME-Liquidchip vs Prosequencing, Sanger sequencing vs Prosequencing were, respectively, 5.25 (p < 0.025), 6.36 (p < 0.025) and 1.01 (p > 0.25).
  2. Wt, wild type; Mut, mutant.