The effect of CTLA-4 A49G polymorphism on rheumatoid arthritis risk: a meta-analysis

Diagnostic Pathology

Table 1 Main characteristics of studies included in our work

First author	Year	Location	Ethnicity	Case/controls			HWE
First author	Year	Location	Ethnicity	GG	GA	AA	HWE
Seidl	1998	Germany	Caucasian	37/68	138/210	83/179	0.88
Matsushita	1999	Japan	Asian	200/56	199/72	62/22	0.98
Gonzalez-Escribano	1999	Spain	Caucasian	10/30	63/103	65/172	0.06
Barton	2000	Spain	Caucasian	14/12	57/70	65/62	0.44
Yanagawa	2000	Japan	Asian	29/78	50/88	6/34	0.56
Hadj	2001	Tunisia	African	23/68	27/62	10/20	0.33
Milicic	2001	UK	Caucasian	63/73	223/213	135/166	0.94
Lee	2002	Korea	Asian	41/49	35/29	10/8	0.49
Vaidya	2002	UK	Caucasian	20/45	65/158	38/146	0.97
Lee	2003	China	Asian	103/85	67/100	16/18	0.32
Liu	2004	Taiwan	Asian	14/21	42/50	9/10	0.07
Barton	2004	UK	Caucasian	34/29	55/68	43/59	0.49
Lei	2005	China	Asian	148/86	138/125	40/39	0.84
Takeuchi	2006	Japan	Asian	49/44	39/49	12/11	0.88
Suppiah	2006	UK	Caucasian	40/92	144/241	92/142	0.85
Tsukahara	2008	Japan	Asian	636/181	668/194	186/73	0.23
Walker	2009	Canada	Caucasian	177/179	554/576	409/493	0.87
Munoz-Valle	2010	Mexico	Mexican	42/34	102/82	55/83	0.22
Plant (F)	2010	France	Caucasian	96/15	315/75	273/72	0.77
Plant (Ge)	2010	Germany	Caucasian	37/94	111/83	72/83	0.44
Plant (Gr)	2010	Greece	Caucasian	26/33	133/107	113/147	0.15
Plant (U)	2010	UK	Caucasian	146/410	451/1255	407/994	0.91
Benhatchi	2011	Slovakia	Caucasian	6/5	33/25	18/21	0.82
Rocha	2011	Brail	Caucasian	9/3	29/15	32/12	0.86
Tang	2013	China	Asian	652/474	642/535	195/191	0.154
Alfadhli	2013	Kuwait	Asian	10/14	30/86	74/182	0.65
Liu	2013	China	Asian	77/130	111/125	25/48	0.16

ISSN: 1746-1596