Table 1 Clinicopathological features and miR-130b expression in HCC
miR-130b expression level | ||||
|---|---|---|---|---|
Clinicopathologic variables | Number of cases | Low expression | High expression | P value |
Age | ||||
<50 | 46 | 25 | 21 | |
≥50 | 51 | 23 | 28 | 0.81 |
Gender | ||||
Male | 59 | 29 | 30 | |
Female | 38 | 19 | 19 | 0.85 |
HBsAg | ||||
Postive | 61 | 20 | 41 | |
Negtive | 36 | 28 | 8 | 0.02 |
AFP (ng/ml) | ||||
<25 | 48 | 38 | 10 | |
≥25 | 49 | 10 | 39 | 0.04 |
Tumor size (cm) | ||||
<5 | 52 | 40 | 12 | |
≥5 | 45 | 8 | 37 | 0.04 |
Histologic grade | ||||
High | 33 | 4 | 29 | |
Low | 64 | 44 | 20 | 0.005 |
Tumor number | ||||
Solitary | 61 | 34 | 27 | |
Multiple | 36 | 14 | 22 | 0.08 |
Vein invasion | ||||
Presence | 36 | 17 | 19 | |
Absence | 61 | 31 | 30 | 0.41 |
TNM stage | ||||
I-II | 52 | 44 | 8 | |
III–IV | 45 | 4 | 41 | <0.001 |