Table 2 Multivariate analyses for relapse-free survival and overall survival by Cox regression model

Age

1.06

0.23-2.35

0.57

1.21

0.35-1.30

0.23

TNM stage

3.29

0.89-7.23

0.06

4.24

3.21-9.22

0.01*

Tumor grade

2.98

1.29-6.77

0.009*

3.83

0.87-4.91

0.08

Histological type

0.81

0.27-3.23

0.62

0.91

0.37-1.29

0.36

Lymph node metastasis

2.21

0.98-8.22

0.07

3.12

2.46-10.92

0.007*

ER

1.28

0.82-2.33

0.29

1.81

0.23-3.11

0.63

PR

1.87

0.28-2.99

0.32

1.34

0.38-3.10

0.29

HER2

2.29

1.88-4.83

0.02*

2.12

0.91-3.91

0.06

DKK-1 expression

3.97

1.82-10.99

<0.001*

2.19

1.28-9.24

0.002*