Table 2 Relationship between immunochemical features and disease status

VEGFA

APOE

1

47 (28.7%)

12 (16.2%)

0.115

1

30 (15.5%)

36 (50.7%)

<0.0001

2

2

44 (22.8%)

22 (31.0%)

3

3

54 (28.0%)

12 (16.9%)

4

4

65 (33.7%)

1 (1.4%)

MMP9

SERPINA1

1

14 (7.7%)

50 (67.6%)

<0.0001

1

35 (18.8%)

30 (40.5%)

<0.0001

2

47 (25.8%)

17 (23.0%)

2

40 (21.5%)

25 (33.8%)

3

60 (33.0%)

4 (5.4%)

3

49 (26.3%)

16 (21.6%)

4

61 (33.5%)

3 (4.1%)

4

62 (33.3%)

3 (4.1%)

MMP10

SDC1

1

37 (20.2%)

27 (36.5%)

<0.0001

1

27 (14.6%)

36 (51.4%)

<0.0001

2

36 (19.7%)

28 (37.8%)

2

35 (18.9%)

29 (41.4%)

3

46 (25.1%)

18 (24.3%)

3

60 (32.4%)

4 (5.7%)

4

64 (35.0%)

1 (1.4%)

4

63 (34.1%)

1 (1.4%)

SERPINE1

ANG

1

47 (25.7%)

16 (22.2%)

<0.0001

1

4 (2.1%)

62 (86.1%)

<0.0001

2

31 (16.9%)

33 (45.8%)

2

56 (29.0%)

10 (13.9%)

3

46 (25.1%)

18 (25.0%)

3

66 (34.2%)

0 (0%)

4

59 (32.2%)

5 (6.9%)

4

67 (34.7%)

0 (0%)

IL8

1

56 (28.6%)

10 (24.3%)

<0.0001

2

43 (21.9%)

24 (34.3%)

3

36 (18.4%)

30 (32.9%)

4

61 (31.1%)

6 (8.6%)

CA9

1

35 (17.9%)

31 (44.3%)

<0.0001

2

49 (25.0%)

18 (25.7%)

3

48 (24.5%)

18 (25.7%)

4

64 (32.7%)

3 (4.3%)