From: Partner of Sld five 3: a potential prognostic biomarker for colorectal cancer
Variables | Total | PSF3 expression | P-value | |
---|---|---|---|---|
Low level | High level | |||
No. of patients | 137 | 66 | 71 | |
Age in years, mean × SD (range) | 61.2 × 7.6 (37"86) | 59.4 × 7.1 (37"81) | 63.5 × 8.8 (42"86) | 0.634 |
Gender, M/F | 89/48 | 42/24 | 47/24 | 0.728 |
Tumor size | 0.013* | |||
<5 cm | 105 | 55 | 50 | |
≥5 cm | 32 | 11 | 21 | |
Depth of wall invasion | 0.006* | |||
Tis-T2 | 81 | 43 | 38 | |
T3-T4 | 56 | 23 | 33 | |
Lymph node metastasis | 0.047* | |||
Negative | 76 | 39 | 37 | |
Positive | 61 | 27 | 34 | |
Distant metastasis | 0.125 | |||
No | 118 | 58 | 60 | |
Yes | 19 | 8 | 11 | |
TNM stage | 0.008* | |||
I/II/III/IV | 46/54/22/15 | 28/26/8/4 | 18/28/14/11 | |
Differentiation | 0.021* | |||
Well/Moderate | 94 | 52 | 42 | |
Poor | 43 | 14 | 29 | |
Adjuvant chemotherapy | 0.079 | |||
Yes | 42 | 22 | 20 | |
No | 95 | 44 | 51 | |
Five-year survival | 0.002* | |||
Yes | 58 | 35 | 23 | |
No | 79 | 31 | 48 |