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Table 2 Morphological and biomechanical properties of rat thoracic aorta with diabetes or valsartan treatment

From: Valsartan blocks thrombospondin/transforming growth factor/Smads to inhibit aortic remodeling in diabetic rats

Groups

Dd (mm)

Ds (mm)

Ps (mmHg)

Pd (mmHg)

DC (1/kPa)

CC (mm 2 /kPa)

Control

1.58 ± 0.14

1.86 ± 0.22

82.67 ± 19.472

64.00 ± 20.993

0.18 ± 0.10

0.48 ± 0.21

Diabetic

1.86 ± 0.18**

2.18 ± 0.18**

97.37 ± 15.011*

71.50 ± 13.135

0.11 ± 0.05*

0.33 ± 0.17*

Valsartan

1.75 ± 0.18*

2.08 ± 0.17*

71.22 ± 19.642△

54.89 ± 19.161△

0.24 ± 0.14△

0.53 ± 0.31△

  1. Abbreviations: CC compliance coefficient, DC distensibility coefficient, Dd diastolic diameter, Ds systolic diameter.
  2. * P < 0.05 vs control; ** P < 0.01 vs control; ∆ P < 0.05 vs diabetic.
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Diagnostic Pathology

ISSN: 1746-1596

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