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Table 3 Frequencies of several abnormalities detected in non-clonal cytopenias and MDS

From: Improving the differential diagnosis between myelodysplastic syndromes and reactive peripheral cytopenias by multiparametric flow cytometry: the role of B-cell precursors

Alterations Reactive cytopenias (n = 35) MDS low risk <5%BM blast (n = 42) MDS high risk >5% BM blast (n = 12) p value for X 2
Granulocytic series     
Abnormal granularity 0 17 3 0.001
Abnormal decrease in CD45 expression 3 9 1 0.245
Abnormal pattern in CD13/CD16 2 23 8 0.0001
Abnormal pattern in CD33/HLA-DR 7 26 9 0.0001
Expression of CD56 0 9 1 0.018
Aberrant expression of CD34 1 7 3 0.06
Aberrant expression of CD7 1 2 1 0.776
Aberrant expression of CD19 0 4 0 0.101
Asynchronous shift to the left 7 11 6 0,227
Monocytes series     
Abnormal granularity 7 12 0 0.10
Abnormal % Monocytes 11 27 9 0.04
Increase of % Monocytes CD16+ 8 19 8 0.015
Abnormal pattern in CD33/HLA-DR 5 21 2 0.01
Expression of CD56 6 14 3 0.20
Aberrant expression of CD34 1 17 6 <0.0001
Aberrant expression of CD7 1 9 5 0.008
Aberrant expression of CD19 1 5 2 0.278
Cells in the blast gate     
Increase of % CD34+ cells 1 11 10 <0.0001
Increase of % CD34+/CD13+/CD117+ 4 18 9 0.001
Anomalous expression of CD7 0 9 8 <0.0001
Anomalous expression of CD56 2 15 9 <0.0001