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Figure 1 | Diagnostic Pathology

Figure 1

From: MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma

Figure 1

Normalized expression of analyzed miRNAs in control pancreatic tissue, CP tissue and PDAC tissue. A) MiR-198 is increased in PDAC compared to CP tissue (P = 0.0003; CP) and healthy pancreas (P < 0.0001; HP). B) MiR-217 is down-regulated in PDAC compared to CP tissue (P = 0.0307; CP) and healthy pancreas (P = 0.0001; HP). C) MiR-21 is up-regulated in PDAC compared to CP tissue (P < 0.0001; CP) and healthy pancreas (P = 0.0018; HP). D) MiR-34a is up-regulated in PDAC compared to CP tissue (P < 0.0001; CP) and healthy pancreas (P = 0.0111; HP). *P < 0.05; **P < 0.001; ***P < 0.0001.

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