MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma

Table 2 The detail results of Kaplan-Meier survival analysis

miRNA	2 ^-dCt value (DFS)	Median DFS	P-value	2 ^-dCt value (OS)	Median OS	P-value
miR-21	< 22.68	14.2 months	0.0011	<27.15	19.1 months	0.0427
miR-21	>22.68	7.5 months	0.0011	>27.15	15.2 months	0.0427
miR-198	<0.01208	15.3 months	0.0001	<0.01393	22.6 months	0.0097
miR-198	>0.01208	9.5 months	0.0001	>0.01393	15.2 months	0.0097
miR-34a	<2.178	9.6 months	0.7186	<2.421	14.9 months	0.9320
miR-34a	>2.178	11.5 months	0.7186	>2.421	16.9 months	0.9320
miR-217	<0.08092	9.6 months	0.1716	<0.06097	14.9 months	0.1370
miR-217	>0.08092	12.2 months	0.1716	>0.06087	21.5 months	0.1370
miR-21/miR-198	low levels of both miRNAs^a	18.2 months	<0.0001	low levels of both miRNAs^b	23.7 months	0.0015
miR-21/miR-198	high level of one/both miRNAs^c	8 months	<0.0001	high level of one/both miRNAs^d	14.9 months	0.0015

^alow levels of both miRNAs = level of miR-21 < 22.68 and level of miR-198 < 0.01208.
^blow levels of both miRNAs = level of miR-21 < 27.15 and level of miR-198 < 0.01393.
^chigh level of one/both miRNAs = level of miR-21 > 22.68 or/and level of miR-198 > 0.01208.
^dhigh level of one/both miRNAs = level of miR-21 > 27.15 or/and level of miR-198 > 0.01393.

ISSN: 1746-1596