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Table 2 Association between clinicopathological characteristics and three groups defined with cluster analysis

From: Assessment of a panel of tumor markers for the differential diagnosis of benign and malignant effusions by well-based reverse phase protein array

  

Category a

 

P value

 

1 No. (%)

2 No. (%)

3 No. (%)

Group

42

25

43

 

Malignant

0 (0.0)

25 (59.5)

17 (40.5)

<0.001

Probable malignantb

19 (59.4)

0 (0.0)

13 (40.6)

 

Benign

23 (63.9)

0 (0.0)

13 (36.1)

 

Fluid

    

Ascites

19 (50.0)

8 (21.1)

11 (28.9)

0.155

Pleural effusion

23 (31.9)

17 (23.6)

32 (44.4)

 

Cytology result

    

Positive

0 (0.0)

25 (59.5)

17 (40.5)

<0.001

Negative

42 (61.8)

0 (0.0)

26 (38.2)

 

Etiology (cancer)

    

Breast

2 (33.3)

2 (33.3)

2 (33.3)

<0.001

Colon

9 (60.0)

1 (6.7)

5 (33.3)

 

Lung

4 (15.4)

11 (42.3)

11 (42.3)

 

Ovary

0 (0.0)

9 (60.0)

6 (40.0)

 

Others

4 (30.8)

2 (15.4)

7 (53.8)

 

Etiology

    

Heart failure

5 (55.6)

0 (0.0)

4 (44.4)

0.002

Liver cirrhosis

13 (81.3)

0 (0.0)

3 (18.8)

 

Inflammatory

5 (50.0)

0 (0.0)

5 (50.0)

 
  1. aThe remaining 4 cases were not categorized into any grouping
  2. bNo malignant effusion but history of malignancy