Table 4 Pathological features of confirmed IgG4-TIN, high-probability IgG4-TIN and both excluded groups in abundant plasma cells samples

Inflammation infiltrating renal capsule

4 (33.3 )

11 (25.6)

0.594

1 (50)

3 (30)

0.584

Inflammation infiltrating renal medulla

6 (50)

23 (53.5)

0.831

1 (50)

5 (50)

1.000

Isolated fibrosis

6 (50)

3 (7)

0.000

2 (100)

4 (40)

0.121

Collagenous fibrosis

8 (66.7)

7 (16.3)

0.001

2 (100)

6 (60)

0.273

Storiform fibrosis

3 (25)

1 (2.3)

0.007

2 (100)

1 (10)

0.007

Lymphoid follicles

2 (16.7)

1 (2.3)

0.053

0 (0)

2 (20)

0.488

Granulomatous lesions

1 (8.3)

0 (0)

0.056

0 (0)

1 (10)

0.640

Necrotizing angiitis

1 (8.3)

1 (2.3)

0.326

0 (0)

1 (10)

0.640

Obliterative phlebitis

0 (0)

0 (0)

--

0 (0)

0 (0)

--

Eosinophil infiltration

8 (66.7)

18 (41.9)

0.128

2 (100)

6 (60)

0.273

Neutrophil infiltration

6 (50)

14 (32.6)

0.267

1 (50)

5 (50)

1.000

Tubulitis

9 (75)

16 (37.2)

0.020

2 (100)

7 (70)

0.371

Peritubular capillaritis

3 (25)

13 (30.2)

0.724

1 (50)

2 (20)

0.371

Tubular necrosis

8 (66.7)

18 (41.9)

0.128

0 (0)

8 (80)

0.091

TBM immune complex deposits

9 (75)

12 (27.9)

0.006

2 (100)

7 (70)

0.371