Table 2 Genotype and allele frequencies of APOA1 gene polymorphisms (-75 G/A and +83 C/T) among CAD cases and healthy controls
Cases (n = 300) | Controls (n = 300) | OR (95%CI) | P | |
|---|---|---|---|---|
Genotype | ||||
GG | 175(58.3) | 161(53.7) | 1.00(Reference) | |
GA | 104(34.7) | 100(33.3) | 0.96(0.68,1.36) | 0.80 |
AA | 21(7.0) | 39(13.0) | 0.50(0.28,0.88) | 0.02 |
CC | 221(73.7) | 230(76.7) | 1.00(Reference) | |
CT | 54(18.0) | 39(13.0) | 1.44(0.92,2.26) | 0.11 |
TT | 25(8.3) | 31(10.3) | 0.84(0.48,1.47) | 0.54 |
Allele | ||||
G | 454(75.7) | 422(70.3) | 1.00(Reference) | |
A | 146(24.3) | 178(29.7) | 0.76(0.59,0.98) | 0.04 |
C | 496(82.7) | 499(83.2) | 1.00(Reference) | |
T | 104(17.3) | 101(16.8) | 1.04(0.77,1.40) | 0.82 |