Table 2 Univariate Cox regression analyses for OS and RFS in HCCs

Age

0.678 (0.420–1.096)

0.113

0.653 (0.409–1.041)

0.073

Gender

2.297 (0.562–9.390)

0.247

2.526 (0.619–10.316)

0.197

HBsAg

3.379 (1.061–10.763)

0.039

3.581 (1.126–11.394)

0.031

AFP

2.187 (1.246–3.839)

0.006

2.000 (1.171–3.418)

0.011

Cirrhosis

1.025 (0.549–1.916)

0.937

1.127 (0.605–2.097)

0.707

Tumor size

2.161 (1.279–3.653)

0.004

1.870 (1.135–3.081)

0.014

Tumor number

2.475 (1.488–4.118)

<0.001

2.576 (1.574–4.216)

<0.001

Tumor encapsulation

0.674 (0.392–1.161)

0.155

0.722 (0.429–1.215)

0.221

Vascular invasion

6.074 (3.449–10.698)

<0.001

5.722 (3.236–10.119)

<0.001

Edmondson-Steiner

1.348 (0.832–2.186)

0.225

1.296 (0.810–2.074)

0.279

TNM stage

4.919 (3.014–8.082)

<0.001

4.282 (2.654–6.907)

<0.001

ITPKA expression

2.579 (1.567–4.245)

<0.001

2.669 (1.638–4.349)

<0.001