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Table 1 Association PAK4 expression with clinicopathological features of human cervical cancer

From: PAK4 confers the malignance of cervical cancers and contributes to the cisplatin-resistance in cervical cancer cells via PI3K/AKT pathway

Characteristics

No. (n = 95)

High PAK4

Low PAK4

P value

N

%

N

%

 

Age (years)

93

    

0.42131

 <65

56

24

55.81

32

64.00

 

 ≥65

37

19

44.19

18

36.00

 

Tumor size (cm)

     

0.59763

 <4

46

20

46.51

26

52.00

 

 ≥4

47

23

53.49

24

48.00

 

HPV

     

0.99205

 Positive

67

31

72.09

36

72.00

 

 Negative

26

12

27.91

14

28.00

 

Tumor histology

     

0.25219

 Squamous

68

29

67.44

39

78.00

 

 Adenocarcinoma

25

14

32.56

11

22.00

 

FIGO stage

     

0.02888*

 Ib

24

6

13.95

18

36.00

 

 IIa

20

8

18.60

12

24.00

 

 IIb

25

13

30.23

12

24.00

 

 IIIa

24

16

37.21

8

16.00

 

LN metastasis

     

0.00525

 Positive

38

24

55.81

14

27.45

 

 Negative

56

19

44.19

37

72.55

 

Distant metastasis

     

0.02105

 Positive

26

17

39.53

9

18.00

 

 Negative

67

26

60.47

41

82.00

 

Histological grade

     

0.03464

 Poor

41

24

55.81

17

34.00

 

 Well/moderade

52

19

44.19

33

66.00

 
  1. *: with significance