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Table 2 Univariate analysis of prognostic factors in cervical cancer patients

From: PAK4 confers the malignance of cervical cancers and contributes to the cisplatin-resistance in cervical cancer cells via PI3K/AKT pathway

Variables Univariable analysis
Hazard ratio 95 % Confidence Interval P value
Age    
  < 65 vs ≥ 65 1.261 (0.714-1.906) 0.4362
Tumor size (cm)    
  < 4 vs ≥4 1.179 (0.706-1.942) 0.4523
HPV    
 Positive vs Negative 0.875 (0.437-1.691) 0.7831
Tumor histology    
 Squamous vs Others 0.696 (0.354-1.342) 0.2874
FIGO stage    
 Ib-IIa vs IIb-IIIa 2.226 (1.416-3.752) 0.0026*
LN metastasis    
 Positive vs Negative 2.042 (1.318-3.265) 0.0048
Distant metastasis    
 Positive vs Negative 1.660 (0.980-2.945) 0.0522
Histological grade    
 Poor vs Well/moderate 1.762 (1.130-2.706) 0.0375
PAK4 expression    
 High vs Low 2.217 (1.435-3.562) 0.0014
  1. *: with significance