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Table 5 Results of univariate analyses of overall survival (OS) time

From: Evaluation of the correlation of KAI1/CD82, CD44, MMP7 and β-catenin in the prediction of prognosis and metastasis in colorectal carcinoma

Variables

n

Mean OS

P-value

Log-Rank

(months)

β-catenin

  

<0.001

15.756

 Negative

45

66.1 ± 22.6

  

 Positive

129

46.8 ± 23.0

  

KAI1/CD82

  

<0.001

46.961

 Negative

118

42.9 ± 21.8

  

 Positive

56

70.5 ± 18.1

  

CD44

  

<0.001

24.611

 Negative

68

64.4 ± 22.3

  

 Positive

106

43.7 ± 22.2

  

MMP7

  

<0.001

27.764

 Negative

61

67.5 ± 20.3

  

 Positive

113

43.3 ± 22.1

  

Sex

  

0.804

0.062

 Male

101

53.7 ± 23.0

  

 Female

73

49.1 ± 26.0

  

Age

   

0.057

 60 years

68

52.7 ± 23.1

0.811

 

  ≥ 60 years

106

51.2 ± 25.3

  

Diameter of tumor

  

0.448

0.575

 5.0 cm

104

50.9 ± 24.1

  

  ≥ 5.0 cm

70

53.6 ± 24.8

  

Location

  

0.217

1.521

 Rectum

89

50.3 ± 25.7

  

 Colon

85

53.3 ± 22.9

  

Differentiation

  

0.628

0.931

 Well

39

55.7 ± 25.5

  

 Moderate

90

51.4 ± 23.9

  

 Poor

45

49.1 ± 24.4

  

Depth of invasion

  

0.005

7.781

 Under serous membrane

96

57.1 ± 23.9

  

 To serous membrane

78

45.2 ± 23.4

  

Lymph node metastasis

  

<0.001

24.355

 Negative

103

60.9 ± 20.3

  

 Positive

71

38.5 ± 23.7

  

Distant metastasis

  

0.003

8.818

 Negative

150

54.1 ± 24.1

  

 Positive

24

37.2 ± 21.0

  

TNM stage

  

<0.001

52.689

 I+ II

101

62.3 ± 19.7

  

 III + IV

73

37.2 ± 22.7