Table 1 Patient demographics
From: High expression of TAZ indicates a poor prognosis in retinoblastoma
Characteristic | No. of patients n = 43, n (%) |
|---|---|
Patients | 43 (100) |
Age at presentation (y) | |
< 5 y | 39 (90.7) |
≥ 5 y | 4 (9.3) |
Gender | |
Male | 18 (41.9) |
Female | 25 (58.1) |
Hereditary pattern | |
Sporadic | 42 (97.7) |
Familial | 1 (2.3) |
Laterality | |
Unilateral | 34 (79.1) |
Bilateral | 9 (20.9) |
Unilateral (n = 34) | |
Right | 21 (61.8) |
Left | 13 (38.2) |
First clinical presenting signs | |
Leucocoria | 34 (79.1) |
Strabismus | 5 (11.6) |
Proptosis | 3 (7.0) |
Swelling | 1 (2.3) |
cTNM clinical classification | |
T classification | |
T1 | 10 (23.3) |
T2 | 14 (32.6) |
T3 | 11 (25.6) |
T4 | 8 (18.6) |
N classification | |
N0 | 20 (46.5) |
N1 | 17 (39.5) |
N2 | 6 (14.0) |
M classification | |
M0 | 31 (72.1) |
M1 | 12 (27.9) |
cTNM stage | |
I | 2 (4.7) |
II | 12 (27.9) |
III | 17 (39.5) |
IV | 12 (27.9) |
Largest tumor base (mm), mean (median, range) | 11.3 (5–26) |
≤ 15 mm | 28 (58.1) |
> 15 mm | 15 (41.9) |
Tumor thickness (mm), mean (median, range) | 8.6 (9, 3–16) |
≤ 10 mm | 25 (58.1) |
> 10 mm | 18 (41.9) |
Growth pattern | |
Endophytic | 12 (27.9) |
Exophytic | 20 (46.5) |
Mixed | 5 (11.6) |
Diffuse infiltrating | 6 (14.0) |
Differentiation | |
Well | 9 (20.9) |
Moderate | 15 (34.9) |
Poorly | 19 (44.2) |
Treatment | |
Eye enucleated | 19 (44.2) |
Enucleated + chemotherapy | 22 (51.2) |
Enucleated + chemotherapy + radiation therapy | 2 (4.7) |
Outcomes | |
Death | 14 (32.6) |
Survival | 29 (67.4) |